diff --git a/qmake/qmakelibraryinfo.cpp b/qmake/qmakelibraryinfo.cpp
index 581d1ad086..273da190d4 100644
--- a/qmake/qmakelibraryinfo.cpp
+++ b/qmake/qmakelibraryinfo.cpp
@@ -156,14 +156,8 @@ static QString getHostPrefixFromHostBinDir()
     return getPrefixFromHostBinDir(QT_CONFIGURE_HOSTBINDIR_TO_HOSTPREFIX_PATH);
 }
 
-static QString getPrefix(QMakeLibraryInfo::PathGroup group)
+static QString getPrefix()
 {
-#if QT_CONFIGURE_CROSSBUILD
-    if (group == QMakeLibraryInfo::DevicePaths)
-        return QString::fromLocal8Bit(QT_CONFIGURE_PREFIX_PATH);
-#else
-    Q_UNUSED(group);
-#endif
     return getExtPrefixFromHostBinDir();
 }
 
@@ -268,7 +262,7 @@ QString QMakeLibraryInfo::rawLocation(int loc, QMakeLibraryInfo::PathGroup group
         // strlen is meaningless.
         const char *volatile path = nullptr;
         if (loc == QLibraryInfo::PrefixPath) {
-            ret = getPrefix(group);
+            ret = getPrefix();
         } else if (unsigned(loc)
                    <= sizeof(qt_configure_str_offsets) / sizeof(qt_configure_str_offsets[0])) {
             path = qt_configure_strs + qt_configure_str_offsets[loc - 1];
diff --git a/src/corelib/global/qconfig.cpp.in b/src/corelib/global/qconfig.cpp.in
index d61b94c806..ddfe1c65e1 100644
--- a/src/corelib/global/qconfig.cpp.in
+++ b/src/corelib/global/qconfig.cpp.in
@@ -38,10 +38,6 @@ static const char qt_configure_strs[] =
 #define QT_CONFIGURE_LIBLOCATION_TO_PREFIX_PATH "@QT_CONFIGURE_LIBLOCATION_TO_PREFIX_PATH@"
 #define QT_CONFIGURE_HOSTBINDIR_TO_EXTPREFIX_PATH "@QT_CONFIGURE_HOSTBINDIR_TO_EXTPREFIX_PATH@"
 #define QT_CONFIGURE_HOSTBINDIR_TO_HOSTPREFIX_PATH "@QT_CONFIGURE_HOSTBINDIR_TO_HOSTPREFIX_PATH@"
-#ifdef QT_BUILD_QMAKE
-# define QT_CONFIGURE_CROSSBUILD 0
-# define QT_CONFIGURE_SYSROOTIFY_PREFIX false
-#endif
 #define QT_CONFIGURE_PREFIX_PATH qt_configure_prefix_path_str + 12
 #ifdef QT_BUILD_QMAKE
 # define QT_CONFIGURE_EXT_PREFIX_PATH qt_configure_ext_prefix_path_str + 12