diff --git a/src/widgets/itemviews/qabstractitemview.cpp b/src/widgets/itemviews/qabstractitemview.cpp
index 8a923e44a7..cfb6a3151a 100644
--- a/src/widgets/itemviews/qabstractitemview.cpp
+++ b/src/widgets/itemviews/qabstractitemview.cpp
@@ -224,7 +224,11 @@ void QAbstractItemViewPrivate::_q_scrollerStateChanged()
             // restore the old selection if we really start scrolling
             if (q->selectionModel()) {
                 q->selectionModel()->select(oldSelection, QItemSelectionModel::ClearAndSelect);
+                // block autoScroll logic while we are already handling scrolling
+                const bool wasAutoScroll = autoScroll;
+                autoScroll = false;
                 q->selectionModel()->setCurrentIndex(oldCurrent, QItemSelectionModel::NoUpdate);
+                autoScroll = wasAutoScroll;
             }
             Q_FALLTHROUGH();
 
diff --git a/tests/auto/widgets/itemviews/qabstractitemview/tst_qabstractitemview.cpp b/tests/auto/widgets/itemviews/qabstractitemview/tst_qabstractitemview.cpp
index 69fac4bd96..e5b24b1a9b 100644
--- a/tests/auto/widgets/itemviews/qabstractitemview/tst_qabstractitemview.cpp
+++ b/tests/auto/widgets/itemviews/qabstractitemview/tst_qabstractitemview.cpp
@@ -35,11 +35,13 @@
 #include <QHeaderView>
 #include <QIdentityProxyModel>
 #include <QItemDelegate>
+#include <QLabel>
 #include <QLineEdit>
 #include <QListWidget>
 #include <QProxyStyle>
 #include <QPushButton>
 #include <QScrollBar>
+#include <QScroller>
 #include <QSignalSpy>
 #include <QSortFilterProxyModel>
 #include <QSpinBox>
@@ -160,6 +162,7 @@ private slots:
     void selectionCommand();
     void mouseSelection_data();
     void mouseSelection();
+    void scrollerSmoothScroll();
 
 private:
     static QAbstractItemView *viewFromString(const QByteArray &viewType, QWidget *parent = nullptr)
@@ -2980,5 +2983,64 @@ void tst_QAbstractItemView::mouseSelection()
     QCOMPARE(actualSelected, selectedRows);
 }
 
+/*!
+    Verify that scrolling an autoScroll enabled itemview with a QScroller
+    produces a continuous, smooth scroll without any jumping around due to
+    the currentItem negotiation between QAbstractItemView and QScroller.
+    QTBUG-64543.
+*/
+void tst_QAbstractItemView::scrollerSmoothScroll()
+{
+    QListWidget view;
+    view.setAutoScroll(true);
+    view.setVerticalScrollMode(QListView::ScrollPerPixel);
+
+    QScroller::grabGesture(view.viewport(), QScroller::TouchGesture);
+    QScroller::grabGesture(view.viewport(), QScroller::LeftMouseButtonGesture);
+
+    for (int i = 0; i < 50; i++) {
+        QListWidgetItem* item = new QListWidgetItem("item " + QString::number(i), &view);
+        // gives items a touch friendly size so that only a few fit into the viewport
+        item->setSizeHint(QSize(100,50));
+    }
+
+    // make sure we have space for only a few items
+    view.setFixedSize(120, 200);
+    view.show();
+    QVERIFY(QTest::qWaitForWindowActive(&view));
+
+    // we flick up, so we should never scroll back
+    int lastScrollPosition = 0;
+    bool scrollBack = false;
+    connect(view.verticalScrollBar(), &QScrollBar::valueChanged, [&](int value){
+        scrollBack |= (value < lastScrollPosition);
+        lastScrollPosition = value;
+    });
+
+    // start in the middle
+    view.scrollToItem(view.item(25));
+    QCOMPARE(view.currentItem(), view.item(0));
+    QListWidgetItem *pressItem = view.item(23);
+    QPoint dragPosition = view.visualRect(view.indexFromItem(pressItem)).center();
+    // the mouse press changes the current item temporarily, but the press is delayed
+    // by the gesture machinery
+    QTest::mousePress(view.viewport(), Qt::LeftButton, Qt::NoModifier, dragPosition);
+    QTRY_COMPARE(view.currentItem(), pressItem);
+
+    // QAIV will reset the current item when the scroller changes state to Dragging
+    for (int y = 0; y < QApplication::startDragDistance() * 2; ++y) {
+        // gesture recognizer needs some throttling
+        QTest::qWait(10);
+        dragPosition -= QPoint(0, 10);
+        const QPoint globalPos = view.viewport()->mapToGlobal(dragPosition);
+        QMouseEvent mouseMoveEvent(QEvent::MouseMove, dragPosition, dragPosition, globalPos,
+                                    Qt::NoButton, Qt::LeftButton, Qt::NoModifier);
+        QApplication::sendEvent(view.viewport(), &mouseMoveEvent);
+        QVERIFY(!scrollBack);
+    }
+
+    QTest::mouseRelease(view.viewport(), Qt::LeftButton, Qt::NoModifier, dragPosition);
+}
+
 QTEST_MAIN(tst_QAbstractItemView)
 #include "tst_qabstractitemview.moc"