diff --git a/icu4c/source/Doxyfile.in b/icu4c/source/Doxyfile.in
index 6a9c78fcf3..0c3eeb80ac 100644
--- a/icu4c/source/Doxyfile.in
+++ b/icu4c/source/Doxyfile.in
@@ -82,7 +82,7 @@ WARN_LOGFILE           =
 INPUT                  = ./common/unicode/platform.h @srcdir@/common/unicode @srcdir@/i18n/unicode @srcdir@/io/unicode @srcdir@/layout/LEFontInstance.h @srcdir@/layout/LEGlyphStorage.h @srcdir@/layout/LELanguages.h @srcdir@/layout/LEScripts.h @srcdir@/layout/LESwaps.h @srcdir@/layout/LETypes.h @srcdir@/layout/LayoutEngine.h @srcdir@/layoutex/layout
 FILE_PATTERNS          = *.h
 RECURSIVE              = NO
-EXCLUDE                = @srcdir@/common/unicode/urename.h @srcdir@/common/unicode/udraft.h @srcdir@/common/unicode/udeprctd.h  @srcdir@/common/unicode/uobslete.h  
+EXCLUDE                = @srcdir@/common/unicode/urename.h @srcdir@/common/unicode/udraft.h @srcdir@/common/unicode/udeprctd.h @srcdir@/common/unicode/uobslete.h @srcdir@/common/unicode/ppalmos.h  
 EXCLUDE_SYMLINKS       = NO
 EXCLUDE_PATTERNS       = config*.h
 EXAMPLE_PATH           =