diff --git a/icu4c/source/common/resbund.cpp b/icu4c/source/common/resbund.cpp
index 2f994d3322..489f28e3de 100644
--- a/icu4c/source/common/resbund.cpp
+++ b/icu4c/source/common/resbund.cpp
@@ -51,7 +51,6 @@
 #include "mutex.h"
 
 #include "rbdata.h"
-#include "unistrm.h"
 #include "filestrm.h"
 #include "cstring.h"
 #include "uresimp.h"
diff --git a/icu4c/source/i18n/tblcoll.cpp b/icu4c/source/i18n/tblcoll.cpp
index 738cc6d68f..1c52a88c50 100644
--- a/icu4c/source/i18n/tblcoll.cpp
+++ b/icu4c/source/i18n/tblcoll.cpp
@@ -61,10 +61,6 @@
 #include "unicode/resbund.h"
 #include "cmemory.h"
 
-#ifdef _DEBUG
-  #include "unistrm.h"
-#endif
-
 /* global variable ---------------------------------------------------------- */
 
 /*