diff --git a/src/inspector/v8-debugger-agent-impl.cc b/src/inspector/v8-debugger-agent-impl.cc
index eb95125025..b58555c561 100644
--- a/src/inspector/v8-debugger-agent-impl.cc
+++ b/src/inspector/v8-debugger-agent-impl.cc
@@ -194,6 +194,14 @@ void adjustBreakpointLocation(const V8DebuggerScript& script,
                               int* columnNumber) {
   if (*lineNumber < script.startLine() || *lineNumber > script.endLine())
     return;
+  if (*lineNumber == script.startLine() &&
+      *columnNumber < script.startColumn()) {
+    return;
+  }
+  if (*lineNumber == script.endLine() && script.endColumn() < *columnNumber) {
+    return;
+  }
+
   if (hint.isEmpty()) return;
   intptr_t sourceOffset = script.offset(*lineNumber, *columnNumber);
   if (sourceOffset == V8DebuggerScript::kNoOffset) return;
@@ -915,6 +923,13 @@ V8DebuggerAgentImpl::setBreakpointImpl(const String16& breakpointId,
   if (lineNumber < script->startLine() || script->endLine() < lineNumber) {
     return nullptr;
   }
+  if (lineNumber == script->startLine() &&
+      columnNumber < script->startColumn()) {
+    return nullptr;
+  }
+  if (lineNumber == script->endLine() && script->endColumn() < columnNumber) {
+    return nullptr;
+  }
 
   v8::debug::BreakpointId debuggerBreakpointId;
   v8::debug::Location location(lineNumber, columnNumber);
diff --git a/test/inspector/regress/regress-crbug-1183664-expected.txt b/test/inspector/regress/regress-crbug-1183664-expected.txt
new file mode 100644
index 0000000000..8a0dac1132
--- /dev/null
+++ b/test/inspector/regress/regress-crbug-1183664-expected.txt
@@ -0,0 +1,19 @@
+Regression test for crbug.com/1183664
+
+Running test: testMultipleScriptsInSameLineWithSameURL
+Setting breakpoint in first script
+[
+    [0] : {
+        columnNumber : 1
+        lineNumber : 0
+        scriptId : <scriptId>
+    }
+]
+Setting breakpoint in second script
+[
+    [0] : {
+        columnNumber : 65
+        lineNumber : 0
+        scriptId : <scriptId>
+    }
+]
diff --git a/test/inspector/regress/regress-crbug-1183664.js b/test/inspector/regress/regress-crbug-1183664.js
new file mode 100644
index 0000000000..558ff2b2aa
--- /dev/null
+++ b/test/inspector/regress/regress-crbug-1183664.js
@@ -0,0 +1,39 @@
+// Copyright 2021 the V8 project authors. All rights reserved.
+// Use  of this source code is governed by a BSD-style license that can be
+// found in the LICENSE file.
+
+let {session, contextGroup, Protocol} = InspectorTest.start('Regression test for crbug.com/1183664');
+
+const url = 'test://foo.js';
+const lineNumber = 0;
+
+const columnNumber1 = 1;
+contextGroup.addScript(`console.log("FIRST")`, lineNumber, columnNumber1, url);
+const columnNumber2 = 65;
+contextGroup.addScript(`console.log("SECOND")`, lineNumber, columnNumber2, url);
+
+InspectorTest.runAsyncTestSuite([
+  async function testMultipleScriptsInSameLineWithSameURL() {
+    await Protocol.Debugger.enable();
+    InspectorTest.logMessage('Setting breakpoint in first script')
+    {
+      const {result: {breakpointId, locations}} = await Protocol.Debugger.setBreakpointByUrl({
+        url,
+        lineNumber,
+        columnNumber: columnNumber1,
+      });
+      InspectorTest.logMessage(locations);
+      await Protocol.Debugger.removeBreakpoint({breakpointId});
+    }
+    InspectorTest.logMessage('Setting breakpoint in second script')
+    {
+      const {result: {breakpointId, locations}} = await Protocol.Debugger.setBreakpointByUrl({
+        url,
+        lineNumber,
+        columnNumber: columnNumber2,
+      });
+      InspectorTest.logMessage(locations);
+      await Protocol.Debugger.removeBreakpoint({breakpointId});
+    }
+  }
+]);